STAT3 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM8415b
Catalog Number: AC-AM8415b
Size: 80 µl, 400 µl
Isotype: mouse IgG2a,κ
Clone Name: 1200CT146.104.153
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG2a,κ
Clone Name: 1200CT146.104.153
Applications: WB
Datasheet
Request Information
Background:
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Other Names:
Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3, APRF
Target/Specificity:
This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Antigen Type: Recombinant Protein
Gene Name: STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Gene ID: 6774
Primary Accession: P40763
Other Accession: P52631; Q19S50; P42227
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Other Names:
Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3, APRF
Target/Specificity:
This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Antigen Type: Recombinant Protein
Gene Name: STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Gene ID: 6774
Primary Accession: P40763
Other Accession: P52631; Q19S50; P42227
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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