PHLDA3 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP71886
Catalog Number: AC-AP59709
Size: 100 µl
Host: Rabbit
Applications: WB, IP, IF/IC, IHC
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IP, IF/IC, IHC
Datasheet
Request Information
Background:
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Other Names:
PHLDA3; TIH1; Pleckstrin homology-like domain family A member 3; TDAG51/Ipl homolog 1
Antigen Type: synthetic peptide
Antigen Type: PHLDA3
Gene ID: 23612
Primary Accession: Q9Y5J5
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Other Names:
PHLDA3; TIH1; Pleckstrin homology-like domain family A member 3; TDAG51/Ipl homolog 1
Antigen Type: synthetic peptide
Antigen Type: PHLDA3
Gene ID: 23612
Primary Accession: Q9Y5J5
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