Stat4 (phospho Tyr693) Polyclonal Antibody

Stat4 (phospho Tyr693) Polyclonal Antibody

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In stock
SKU
ELK-ES1407
Catalog Number: ELK-ES1407
Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC-p, IP, ELISA
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Background:
signal transducer and activator of transcription 4(STAT4) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],

Alternative Names:
STAT4, Signal transducer and activator of transcription 4

Immunogen: The antiserum was produced against synthesized peptide derived from human STAT4 around the phosphorylation site of Tyr693. AA range:660-709

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 86

GeneID: STAT4

Storage: -20°C/1 year

NOTE: For Research Use Only
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