STAT6 antibody (clone 6C10), anti-human
€435.00
In stock
SKU
AC-AT4067a
Catalog Number: AC-AT4067a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT4067a">Request Information
Background:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Other Names:
Signal transducer and activator of transcription 6, IL-4 Stat, STAT6
Antigen Type:
Recombinant Protein
Gene Name: STAT6
Gene ID: 6778
NCBI Accession: NP_001171549.1;NP_001171550.1;NP_001171551.1;NP_003144.3
Primary Accession: P42226
Other Accession: BC004973
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Other Names:
Signal transducer and activator of transcription 6, IL-4 Stat, STAT6
Antigen Type:
Recombinant Protein
Gene Name: STAT6
Gene ID: 6778
NCBI Accession: NP_001171549.1;NP_001171550.1;NP_001171551.1;NP_003144.3
Primary Accession: P42226
Other Accession: BC004973
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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