STAT6 (clone 7D3), anti-human, mouse, rat, monkey

Background:
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

Research Area: Signal Transduction

Synonyms: STAT6B, STAT6C, D12S1644, IL-4-STAT, STAT6

Immunogen: Purified recombinant fragment of human STAT6 expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage