Stathmin 1 (clone ), anti-human

Background:
sphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear. Stathmin’s role in regulation of the cell cycle causes it to be an oncoprotein named oncoprotein 18 (op18). Stathmin (aka op18) can cause uncontrolled cell proliferation when mutated and not functioning properly. If stathmin is unable to bind to tubulin, it allows for constant microtubule assembly and therefore constant mitotic spindle assembly. With no regulation of the mitotic spindle, the cell cycle is capable of cycling uncontrollably resulting in the unregulated cell growth characteristic of cancer cells.

Alternative Name:
Op18, pp19, STMN1, C1orf215, LAP18, OP18, C1orf215, Lag, LAP 18, LAP18, Leukemia associated phosphoprotein p18, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, OP 18, Op18, p18, p19, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, PR22, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin, Stathmin1, STMN 1, Stmn1, STMN1_HUMAN antibody

Application Dilution:
WB:1:500
ICC:1:100
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Stathmin 1 monoclonal antibody detects endogenous levels of Stathmin 1 protein.

Immunogen:
Synthetic peptide within C-terminus of human Stathmin 1.

MW: 17 kDa

Swiss-Prot: P16949 Human

Purification & Purity:
Protein G purified.

Format:
Mouse IgG2b, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.