STAU1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP18806a
Background:
Staufen is a member of the family of double-stranded RNA(dsRNA)-binding proteins involved in the transport and/orlocalization of mRNAs to different subcellular compartments and/ororganelles. These proteins are characterized by the presence ofmultiple dsRNA-binding domains which are required to bind RNAshaving double-stranded secondary structures. The human homologue ofstaufen encoded by STAU, in addition contains a microtubule-binding domain similar to that of microtubule-associated protein1B, and binds tubulin. The STAU gene product has been shown to bepresent in the cytoplasm in association with the rough endoplasmicreticulum (RER), implicating this protein in the transport of mRNAvia the microtubule network to the RER, the site of translation.Five transcript variants resulting from alternative splicing ofSTAU gene and encoding three isoforms have been described. Three ofthese variants encode the same isoform, however, differ in their5'UTR.
Other Names:
Double-stranded RNA-binding protein Staufen homolog 1, STAU1, STAU
Gene Name: STAU1
Gene ID: 6780
Primary Accession: O95793
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Staufen is a member of the family of double-stranded RNA(dsRNA)-binding proteins involved in the transport and/orlocalization of mRNAs to different subcellular compartments and/ororganelles. These proteins are characterized by the presence ofmultiple dsRNA-binding domains which are required to bind RNAshaving double-stranded secondary structures. The human homologue ofstaufen encoded by STAU, in addition contains a microtubule-binding domain similar to that of microtubule-associated protein1B, and binds tubulin. The STAU gene product has been shown to bepresent in the cytoplasm in association with the rough endoplasmicreticulum (RER), implicating this protein in the transport of mRNAvia the microtubule network to the RER, the site of translation.Five transcript variants resulting from alternative splicing ofSTAU gene and encoding three isoforms have been described. Three ofthese variants encode the same isoform, however, differ in their5'UTR.
Other Names:
Double-stranded RNA-binding protein Staufen homolog 1, STAU1, STAU
Gene Name: STAU1
Gene ID: 6780
Primary Accession: O95793
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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