STC2 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1955b
Catalog Number: AC-AM1955b
Size: 80 µl, 400 µl
Isotype: mouse IgA,k
Clone Name: 339CT13.2.6
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgA,k
Clone Name: 339CT13.2.6
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Other Names:
Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2
Target/Specificity:
This STC2 monoclonal antibody is generated from mouse immunized with STC2 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: STC2
Gene ID: 8614
Primary Accession: O76061
NCBI Accession: NP_003705.1
Other Accession: NP_003705.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Other Names:
Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2
Target/Specificity:
This STC2 monoclonal antibody is generated from mouse immunized with STC2 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: STC2
Gene ID: 8614
Primary Accession: O76061
NCBI Accession: NP_003705.1
Other Accession: NP_003705.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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