STEAP4 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61396
Background:
STAMP2 (SixTransMembrane protein of prostate 2), also known as STEAP4 (STEAP family member 4), TIARP or TNFAIP9, is a 459 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one ferric oxidoreductase domain. Expressed ubiquitously with highest expression in lung, prostate, placenta and heart, STAMP2 functions as a metalloreductase that uses FAD as a cofactor to reduce both Fe3+ and Cu2+ to Fe2+ and Cu1+, respectively. Multiple isoforms of STAMP2 exist due to alternative splicing events. The gene encoding STAMP2 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor, alpha-induced protein 9, STEAP4, STAMP2, TNFAIP9
Application Dilution: WB: 1:500~1:1000
Specificity: STEAP4 polyclonal antibody detects endogenous levels of STEAP4 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 195-240 of Human STEAP4.
MW: ~ 52 kDa
Swis Prot.: Q687X5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
STAMP2 (SixTransMembrane protein of prostate 2), also known as STEAP4 (STEAP family member 4), TIARP or TNFAIP9, is a 459 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one ferric oxidoreductase domain. Expressed ubiquitously with highest expression in lung, prostate, placenta and heart, STAMP2 functions as a metalloreductase that uses FAD as a cofactor to reduce both Fe3+ and Cu2+ to Fe2+ and Cu1+, respectively. Multiple isoforms of STAMP2 exist due to alternative splicing events. The gene encoding STAMP2 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor, alpha-induced protein 9, STEAP4, STAMP2, TNFAIP9
Application Dilution: WB: 1:500~1:1000
Specificity: STEAP4 polyclonal antibody detects endogenous levels of STEAP4 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 195-240 of Human STEAP4.
MW: ~ 52 kDa
Swis Prot.: Q687X5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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