STIM1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP10114b
Background:
This gene encodes a type 1 transmembrane protein thatmediates Ca2+ influx after depletion of intracellular Ca2+ storesby gating of store-operated Ca2+ influx channels (SOCs). It is oneof several genes located in the imprinted gene domain of 11p15.5,an important tumor-suppressor gene region. Alterations in thisregion have been associated with the Beckwith-Wiedemann syndrome,Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung,ovarian, and breast cancer. This gene may play a role inmalignancies and disease that involve this region, as well as earlyhematopoiesis, by mediating attachment to stromal cells. This geneis oriented in a head-to-tail configuration with the ribonucleotidereductase 1 gene (RRM1), with the 3' end of this gene situated 1.6kb from the 5' end of the RRM1 gene.
Other Names:
Stromal interaction molecule 1, STIM1, GOK
Gene Name: STIM1
Gene ID: 6786
Primary Accession: Q13586
Other Accession: NP_003147.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a type 1 transmembrane protein thatmediates Ca2+ influx after depletion of intracellular Ca2+ storesby gating of store-operated Ca2+ influx channels (SOCs). It is oneof several genes located in the imprinted gene domain of 11p15.5,an important tumor-suppressor gene region. Alterations in thisregion have been associated with the Beckwith-Wiedemann syndrome,Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung,ovarian, and breast cancer. This gene may play a role inmalignancies and disease that involve this region, as well as earlyhematopoiesis, by mediating attachment to stromal cells. This geneis oriented in a head-to-tail configuration with the ribonucleotidereductase 1 gene (RRM1), with the 3' end of this gene situated 1.6kb from the 5' end of the RRM1 gene.
Other Names:
Stromal interaction molecule 1, STIM1, GOK
Gene Name: STIM1
Gene ID: 6786
Primary Accession: Q13586
Other Accession: NP_003147.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review