STIP1 antibody (clone 4B6), anti-human
€435.00
In stock
SKU
AC-AT4076a
Catalog Number: AC-AT4076a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, IP
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, IP
Request Information AC-AT4076a">Request Information
Background:
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Other Names:
Stress-induced-phosphoprotein 1, STI1, Hsc70/Hsp90-organizing protein, Hop, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521, STIP1
Antigen Type:
Recombinant Protein
Gene Name: STIP1 (HGNC:11387)
Gene ID: 10963
NCBI Accession: NP_006810.1
Primary Accession: P31948
Other Accession: BC002987
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Other Names:
Stress-induced-phosphoprotein 1, STI1, Hsc70/Hsp90-organizing protein, Hop, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521, STIP1
Antigen Type:
Recombinant Protein
Gene Name: STIP1 (HGNC:11387)
Gene ID: 10963
NCBI Accession: NP_006810.1
Primary Accession: P31948
Other Accession: BC002987
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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