STK11 (clone 4H12), anti-human

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cancers, Endocrine System, Signal Transduction

Description:
STK11 (Serine/threonine-protein kinase 11) is a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Defects in STK11 are a cause of predisposition to benign and maligant tumors including gastrointestinal and testicular cancers (Peutz-Jeghers syndrome).

Alternate Names: Serine/threonine-protein kinase 11, Serine/threonine-protein kinase LKB1, Renal carcinoma antigen NY-REN-19, STK11, LKB1, PJS

Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000;

Accession No.: Q15831, NP_000446

Antigen: Purified recombinant fragment of human STK11 expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.