STK11 Peptide

STK11 Peptide

€100.00
In stock
SKU
350490
Catalog Number: 350490
Size: 0.1 mg
Datasheet
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Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cancers, Endocrine System, Signal Transduction

Alternate Names: Serine/threonine-protein kinase 11; Serine/threonine-protein kinase LKB1; Renal carcinoma antigen NY-REN-19; STK11; LKB1; PJS

Accession No.: Q15831, NP_000446

Description:
STK11, a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Defects in STK11 are a cause of predisposition to benign and maligant tumors including gastrointestinal and testicular cancers (Peutz-Jeghers syndrome).

Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

MW: 2159.6 g/mol

Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200128 is selected from a sequence within the N-term region of human STK11. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Composition:
C95H167N31O24S1

Purity:
> 80% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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