GR (Phospho-Ser203) polyclonal, anti-human, mouse

GR (Phospho-Ser203) polyclonal, anti-human, mouse

€470.00
In stock
SKU
AC-AP52488
Catalog Number: AC-AP54996
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
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Background:
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.

Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL

Antigen Type: synthetic peptide

Antigen Type: NR3C1 (HGNC:7978)
Gene ID: 2908
Primary Accession: P04150
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