STK4 antibody (clone 1D7-8A10), anti-human
€435.00
In stock
SKU
AC-AT4088a
Catalog Number: AC-AT4088a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
Request Information AC-AT4088a">Request Information
Background:
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Other Names:
Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, MST-1, STE20-like kinase MST1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase 4 37kDa subunit, MST1/N, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C, STK4, KRS2, MST1
Antigen Type:
Recombinant Protein
Gene Name: STK4 (HGNC:11408)
Gene ID: 6789
NCBI Accession: NP_006273.1
Primary Accession: Q13043
Other Accession: BC005231
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Other Names:
Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, MST-1, STE20-like kinase MST1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase 4 37kDa subunit, MST1/N, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C, STK4, KRS2, MST1
Antigen Type:
Recombinant Protein
Gene Name: STK4 (HGNC:11408)
Gene ID: 6789
NCBI Accession: NP_006273.1
Primary Accession: Q13043
Other Accession: BC005231
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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