AFG3L2 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP74280
Background:
ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).
Other Names:
AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)
Antigen Type: synthetic peptide
Antigen Type: AFG3L2 {ECO:0000303|PubMed:10395799, ECO:0000312|HGNC:HGNC:315}
Gene ID: 10939
Primary Accession: Q9Y4W6
ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).
Other Names:
AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)
Antigen Type: synthetic peptide
Antigen Type: AFG3L2 {ECO:0000303|PubMed:10395799, ECO:0000312|HGNC:HGNC:315}
Gene ID: 10939
Primary Accession: Q9Y4W6
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