STXBP4 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71149
Background:
Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Alternative Name:
Syntaxin-binding protein 4, Syntaxin 4-interacting protein, STX4-interacting protein, Synip, STXBP4
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: STXBP4 polyclonal antibody detects endogenous levels of STXBP4 protein.
Immunogen:
Recombinant protein of human STXBP4.
MW: ~ 62 kDa
Swis Prot.: Q6ZWJ1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Alternative Name:
Syntaxin-binding protein 4, Syntaxin 4-interacting protein, STX4-interacting protein, Synip, STXBP4
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: STXBP4 polyclonal antibody detects endogenous levels of STXBP4 protein.
Immunogen:
Recombinant protein of human STXBP4.
MW: ~ 62 kDa
Swis Prot.: Q6ZWJ1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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