SUCLA2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70936
Background:
SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit), also known as A-BETA, SCS-betaA or renal carcinoma antigen NY-REN-39, is a 463 amino acid mitochondrial matrix enzyme that belongs to the succinate/malate CoA ligase beta subunit family. Widely expressed, SUCLA2 dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. Defects in SUCLA2 may be involved in a group of autosomal recessive disorders known as Mitochondrial DNA depletion syndromes (MDSs) that are characterized by a decrease in mitochondrial DNA copy numbers in affected tissues.
Alternative Name:
Renal carcinoma antigen NY-REN-39, SCS-betaA, SCS-βA, SCSβA,
Application Dilution: WB: 1:500 - 1:1000
Specificity: SUCLA2 polyclonal antibody detects endogenous levels of SUCLA2 protein.
Immunogen:
Recombinant protein of human SUCLA2.
MW: ~ 50 kDa
Swis Prot.: Q9P2R7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit), also known as A-BETA, SCS-betaA or renal carcinoma antigen NY-REN-39, is a 463 amino acid mitochondrial matrix enzyme that belongs to the succinate/malate CoA ligase beta subunit family. Widely expressed, SUCLA2 dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. Defects in SUCLA2 may be involved in a group of autosomal recessive disorders known as Mitochondrial DNA depletion syndromes (MDSs) that are characterized by a decrease in mitochondrial DNA copy numbers in affected tissues.
Alternative Name:
Renal carcinoma antigen NY-REN-39, SCS-betaA, SCS-βA, SCSβA,
Application Dilution: WB: 1:500 - 1:1000
Specificity: SUCLA2 polyclonal antibody detects endogenous levels of SUCLA2 protein.
Immunogen:
Recombinant protein of human SUCLA2.
MW: ~ 50 kDa
Swis Prot.: Q9P2R7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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