SUMF2 antibody (clone 4B3), anti-human
€435.00
In stock
SKU
AC-AT4104a
Catalog Number: AC-AT4104a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4104a">Request Information
Background:
The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
Sulfatase-modifying factor 2, C-alpha-formylglycine-generating enzyme 2, SUMF2
Antigen Type:
Recombinant Protein
Gene Name: SUMF2 {ECO:0000303|PubMed:15962010, ECO:0000312|HGNC:HGNC:20415}
Gene ID: 25870
NCBI Accession: NP_001035934.2;NP_001035935.2;NP_001123541.1;NP_001139805.1;NP_056226.2
Primary Accession: Q8NBJ7
Other Accession: NM_015411
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
Sulfatase-modifying factor 2, C-alpha-formylglycine-generating enzyme 2, SUMF2
Antigen Type:
Recombinant Protein
Gene Name: SUMF2 {ECO:0000303|PubMed:15962010, ECO:0000312|HGNC:HGNC:20415}
Gene ID: 25870
NCBI Accession: NP_001035934.2;NP_001035935.2;NP_001123541.1;NP_001139805.1;NP_056226.2
Primary Accession: Q8NBJ7
Other Accession: NM_015411
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
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