SUMO2 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP1285b
Background:
SUMO2 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. SUMO2 does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. This protein plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS isoforms 1-4.
Other Names:
Small ubiquitin-related modifier 2-A, SUMO-2-A, sumo2-a, smt3h2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1285b was selected from the C-term region of human Xenopus SUMO2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: sumo2-a
Gene ID: 379777
Primary Accession: Q7ZTK7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SUMO2 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. SUMO2 does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. This protein plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS isoforms 1-4.
Other Names:
Small ubiquitin-related modifier 2-A, SUMO-2-A, sumo2-a, smt3h2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1285b was selected from the C-term region of human Xenopus SUMO2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: sumo2-a
Gene ID: 379777
Primary Accession: Q7ZTK7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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