SUMO2 monoclonal (C-term), anti-human, rat
€0.00
In stock
SKU
AC-AM2225b
Catalog Number: AC-AM2225b
Size: 80 µl, 400 µl
Isotype: mouse IgG2b
Clone Name: 973CT8.1.1
Applications: IF, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: mouse IgG2b
Clone Name: 973CT8.1.1
Applications: IF, WB
Datasheet
Request Information
Background:
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Other Names:
Small ubiquitin-related modifier 2, SUMO-2, HSMT3, SMT3 homolog 2 {ECO:0000312|HGNC:HGNC:11125}, SUMO-3, Sentrin-2, Ubiquitin-like protein SMT3B, Smt3B, SUMO2 (HGNC:11125)
Target/Specificity:
Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: SUMO2 (HGNC:11125)
Gene ID: 6613
Primary Accession: P61956
NCBI Accession: NP_001005849.1;NP_008868.3
Other Accession: P61959; P61958; P61957; Q2PFW2; Q6LDZ8; Q5ZJM9; P61955
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Other Names:
Small ubiquitin-related modifier 2, SUMO-2, HSMT3, SMT3 homolog 2 {ECO:0000312|HGNC:HGNC:11125}, SUMO-3, Sentrin-2, Ubiquitin-like protein SMT3B, Smt3B, SUMO2 (HGNC:11125)
Target/Specificity:
Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: SUMO2 (HGNC:11125)
Gene ID: 6613
Primary Accession: P61956
NCBI Accession: NP_001005849.1;NP_008868.3
Other Accession: P61959; P61958; P61957; Q2PFW2; Q6LDZ8; Q5ZJM9; P61955
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review