SUPV3L1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71382
Background:
SUV3, also known as SUPV3L1 (suppressor of var1, 3-like 1), is a 786 amino acid protein that localizes to both the nucleus and the mitochondrial matrix and contains one helicase C-terminal domain, as well as one helicase ATP-binding domain. Expressed in a broad range of tissues, SUV3 interacts with HBXIP and functions as an ATPase DNA/RNA helicase that uses magnesium as a cofactor to catalyze the unwinding of DNA/RNA and RNA/RNA duplexes, thereby playing a role in DNA replication and transcriptional initiation. SUV3 exhibits optimal activity at a pH of 5 and, in addition to its helicase activity, is thought to protect cells from apoptosis and participate in maintaining mitochondrial homeostasis.
Alternative Name:
SUV3, SUV3-like protein 1
Application Dilution: WB: 1:1000 - 1:4000
Specificity: SUPV3L1 polyclonal antibody detects endogenous levels of SUPV3L1 protein.
Immunogen:
Recombinant protein of human SUPV3L1.
MW: ~ 88 kDa
Swis Prot.: Q8IYB8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SUV3, also known as SUPV3L1 (suppressor of var1, 3-like 1), is a 786 amino acid protein that localizes to both the nucleus and the mitochondrial matrix and contains one helicase C-terminal domain, as well as one helicase ATP-binding domain. Expressed in a broad range of tissues, SUV3 interacts with HBXIP and functions as an ATPase DNA/RNA helicase that uses magnesium as a cofactor to catalyze the unwinding of DNA/RNA and RNA/RNA duplexes, thereby playing a role in DNA replication and transcriptional initiation. SUV3 exhibits optimal activity at a pH of 5 and, in addition to its helicase activity, is thought to protect cells from apoptosis and participate in maintaining mitochondrial homeostasis.
Alternative Name:
SUV3, SUV3-like protein 1
Application Dilution: WB: 1:1000 - 1:4000
Specificity: SUPV3L1 polyclonal antibody detects endogenous levels of SUPV3L1 protein.
Immunogen:
Recombinant protein of human SUPV3L1.
MW: ~ 88 kDa
Swis Prot.: Q8IYB8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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