Survivin Monoclonal Antibody

Background:
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Neuroscience

Synonyms:
API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, Baculoviral IAP repeat-containing protein 5, BIRC 5, BIRC5, BIRC5, EPR 1, IAP4, Survivin variant 3 alpha, SVV, TIAP

Immunogen: Recombinant Protein

Swissprot: O15392
Observed MW: 16 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:1000-2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8808/sc-8809/sc-8807/sc-8806/sc-10811