Survivin (phospho Thr34) Polyclonal Antibody

Background:
baculoviral IAP repeat containing 5(BIRC5) Homo sapiens This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],

Alternative Names:
BIRC5, API4, IAP4, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin

Immunogen: The antiserum was produced against synthesized peptide derived from human Survivin around the phosphorylation site of Thr34. AA range:11-60

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 16

GeneID: BIRC5

Storage: -20°C/1 year

NOTE: For Research Use Only