SUV39H1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS72333
Background:
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
Alternative Name:
H3-K9-HMTase1,KMT1A,MG44,SUV39H
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SUV39H1 polyclonal antibody detects endogenous levels of SUV39H1 protein.
Immunogen:
Recombinant Protein of human SUV39H1
MW: ~ 48 kDa
Swis Prot.: O43463
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
Alternative Name:
H3-K9-HMTase1,KMT1A,MG44,SUV39H
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SUV39H1 polyclonal antibody detects endogenous levels of SUV39H1 protein.
Immunogen:
Recombinant Protein of human SUV39H1
MW: ~ 48 kDa
Swis Prot.: O43463
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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