Synaptobrevin (clone SP10), anti-human, mouse, rat, bovine, hamster
€510.00
In stock
SKU
253220
Catalog Nr.: 253220
Size: 0.1 ml
Isotype: Mouse IgM
Applications: E, WB, IHC
Datasheet
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Size: 0.1 ml
Isotype: Mouse IgM
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: SNAREs
Pathway and Disease: Nervous and Sensory Systems, Cell Communication
Description:
Synaptobrevin (VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer’s disease.
Alternate Names: Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, VAMP1, SYB1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:100
Accession No.: P23763
Antigen: Synaptic immunoprecipitate (crude) from human brain.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Cell Communication
Description:
Synaptobrevin (VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer’s disease.
Alternate Names: Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, VAMP1, SYB1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:100
Accession No.: P23763
Antigen: Synaptic immunoprecipitate (crude) from human brain.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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