Synaptophysin (clone S7), anti-human, mouse, rat
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In stock
SKU
BMA1038
Catalog Number: BMA1038
Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, mouse, rat
Application(s): WB, IHC-P, ICC, Flow-Cyt
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Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, mouse, rat
Application(s): WB, IHC-P, ICC, Flow-Cyt
Request Information
Background:
Synaptophysin, also known as the major synaptic vesicle protein p38,is an integral membrane protein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass, accounting for about 10% of total vesicle protein.1The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses.2
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the TOPO_MOD residues of mouse Synaptophysin.
Recommended Application:
Western Blot, WB (1:100-1:500); Immunohistochemistry, IHC-P(1:20-1:100); Immunocytochemistry, ICC (1:20-1:100); Flow Cytometry, Flow-Cyt (1:20-1:50)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Synaptophysin, also known as the major synaptic vesicle protein p38,is an integral membrane protein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass, accounting for about 10% of total vesicle protein.1The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses.2
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the TOPO_MOD residues of mouse Synaptophysin.
Recommended Application:
Western Blot, WB (1:100-1:500); Immunohistochemistry, IHC-P(1:20-1:100); Immunocytochemistry, ICC (1:20-1:100); Flow Cytometry, Flow-Cyt (1:20-1:50)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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