SYNE3 polyclonal, anti-human
€388.00
In stock
SKU
BS72153
Background:
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Alternative Name:
C14orf139, C14orf49, KASH3, LINC00341, NCRNA00341, NET53, Nesp3, Nesprin3, Nesprin 3, Nesprin-3
Application Dilution: WB: 1:500 - 1:2000
Specificity: SYNE3 polyclonal antibody detects endogenous levels of SYNE3 protein.
Immunogen:
Recombinant Protein of human SYNE3
MW: 112kDa
Swis Prot.: Q6ZMZ3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Alternative Name:
C14orf139, C14orf49, KASH3, LINC00341, NCRNA00341, NET53, Nesp3, Nesprin3, Nesprin 3, Nesprin-3
Application Dilution: WB: 1:500 - 1:2000
Specificity: SYNE3 polyclonal antibody detects endogenous levels of SYNE3 protein.
Immunogen:
Recombinant Protein of human SYNE3
MW: 112kDa
Swis Prot.: Q6ZMZ3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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