Ephrin-B1 (phospho Tyr317) polyclonal, anti-human, mouse, rat

Ephrin-B1 (phospho Tyr317) polyclonal, anti-human, mouse, rat

€470.00
In stock
SKU
AC-AP67288
Catalog Number: AC-AP73623
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
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Background:
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PubMed:8070404, PubMed:7973638). Binding to Eph receptors residing on adjacent cells leads to contact- dependent bidirectional signaling into neighboring cells (PubMed:8070404, PubMed:7973638). Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PubMed:8070404, PubMed:7973638). Can also bind EPHB2 and EPHB3 (PubMed:8070404). Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity). May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Other Names:
EFNB1; EFL3; EPLG2; LERK2; Ephrin-B1; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2

Antigen Type: synthetic peptide

Antigen Type: EFNB1
Gene ID: 1947
Primary Accession: P98172
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