Syntaxin (clone SP8), anti-human, rat, pig, horse
€510.00
In stock
SKU
253224
Catalog Nr.: 253224
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC
Datasheet
Request Information
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: SNAREs
Pathway and Disease: Nervous and Sensory Systems, Cell Communication
Description:
Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have been correlated with schizophrenia.
Alternate Names: Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000 IHC: 1:100
Accession No.: Q16623
Antigen: Synaptic immunoprecipitate (crude) from human brain.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Cell Communication
Description:
Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have been correlated with schizophrenia.
Alternate Names: Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000 IHC: 1:100
Accession No.: Q16623
Antigen: Synaptic immunoprecipitate (crude) from human brain.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review