Syntenin (clone 3D9-G9-H4), anti-human

Background:
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: MDA-9, MDA9, ST1, SYCL, TACIP18

Cellular Location: Cell junction Cell membrane Cytoplasm Endoplasmic reticulum membrane Melanosome Nucleus Peripheral membrane protein adherens junction cytoskeleton cytosol focal adhesion

Immunogen:
Purified recombinant human Syntenin protein fragments expressed in E.coli.

Gene Symbol: Syntenin

Gene ID: 6386

Swiss prot: O00560

Calculated MW: 32kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.