SYP (clone 7H12), anti-human, rat

SYP (clone 7H12), anti-human, rat

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In stock
SKU
BT-MCA2490
Catalog Number: BT-MCA2490
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human, rat
Application(s): WB, IHC
Datasheet
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Background:
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

Research Area: Neuroscience

Synonyms: MRXSYP, SYP

Immunogen: Purified recombinant fragment of SYP expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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