T-Cell Receptor gamma delta (TCR-g/d) (clone 11F2), anti-human

Background:
Two types of T cell antigen receptors (TCRs) are now known, the alpha/beta, and the gamma/delta heterodimer, which are expressed at the cell surface in association with the CD3 molecular complex. TCR-gamma can occur in either disulphide-linked or non-disulphide-linked forms. The gamma/delta T-cell receptor is present on a minor subset of T lymphocytes in peripheral blood, thymus, spleen, and lymph node. In man and Mouse, only a small part of the T lymphocytes of the peripheral blood (<5%) is gamma/delta. gamma/delta T lymphocytes may complement alpha/beta T cells in terms of antigenic specificities, functional capabilities, or sites of action within the body.

Clone: 11F2

Isotype: Mouse IgG1

Source: 11F2 (anti-TCR gamma delta-l) is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 Mouse myeloma cells with spleen cells from a Balb/c mice immunized with protein A-Sepharose/anti-CD3/antigen complex.

Reactivity: human

Specificity: Clone 11F2 recognizes the gamma/delta T-cell receptor (TCR).

Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.

Applications: ELISA, Flow Cytometry, Immunohistochemistry (frozen), Immunoprecipitation

Storage: Store at 4C, or in small aliquots at -20C.