XRCC4 (clone 5C10), anti-human
€470.00
In stock
SKU
AC-AP63340
Background:
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Other Names:
XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
Antigen Type: synthetic peptide
Antigen Type: XRCC4 {ECO:0000303|PubMed:8548796, ECO:0000312|HGNC:HGNC:12831}
Gene ID: 7518
Primary Accession: Q13426
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Other Names:
XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
Antigen Type: synthetic peptide
Antigen Type: XRCC4 {ECO:0000303|PubMed:8548796, ECO:0000312|HGNC:HGNC:12831}
Gene ID: 7518
Primary Accession: Q13426
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