TADA3L antibody (clone 3H3), anti-human
€435.00
In stock
SKU
AC-AT4135a
Catalog Number: AC-AT4135a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4135a">Request Information
Background:
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Other Names:
Transcriptional adapter 3, ADA3 homolog, hADA3, STAF54, Transcriptional adapter 3-like, ADA3-like protein, TADA3, ADA3, TADA3L
Antigen Type:
Recombinant Protein
Gene Name: TADA3
Gene ID: 10474
NCBI Accession: NP_001265199.1;NP_006345.1;NP_597814.1
Primary Accession: O75528
Other Accession: BC013433
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Other Names:
Transcriptional adapter 3, ADA3 homolog, hADA3, STAF54, Transcriptional adapter 3-like, ADA3-like protein, TADA3, ADA3, TADA3L
Antigen Type:
Recombinant Protein
Gene Name: TADA3
Gene ID: 10474
NCBI Accession: NP_001265199.1;NP_006345.1;NP_597814.1
Primary Accession: O75528
Other Accession: BC013433
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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