TADA3L polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7973
Background:
ADA3 (Transcriptional adapter 3-like, STAF54) is a 432 amino acid protein encoded by the human gene TADA3L. ADA3 is a ubiquitously expressed nuclear protein that functions as a component of the PCAF (p300/CBP-associated factor) complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex is the human homolog of the yeast SAGA complex. ADA3 interacts with the E6 gene and is a target of E6-induced degradation. ADA3 binds selectively to the high-risk HPV E6 proteins and immortalization-competent E6 mutants. ADA3 functions as a coactivator for p53-mediated transactivation by stabilizing p53 protein.
Alternative Name:
ADA3, ADA3 homolog, ADA3-like protein, FLJ20221, FLJ21329, hADA3, Transcriptional adaptor 3 (NGG1 homolog yeast) like, Transcriptional adaptor 3 like,
Application Dilution: WB: 1:500~1:2000
Specificity: TADA3L polyclonal antibody detects endogenous levels of TADA3L protein.
Immunogen:
Recombinant full length Human TADA3L.
MW: ~ 49 kDa
Swis Prot.: O75528
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ADA3 (Transcriptional adapter 3-like, STAF54) is a 432 amino acid protein encoded by the human gene TADA3L. ADA3 is a ubiquitously expressed nuclear protein that functions as a component of the PCAF (p300/CBP-associated factor) complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex is the human homolog of the yeast SAGA complex. ADA3 interacts with the E6 gene and is a target of E6-induced degradation. ADA3 binds selectively to the high-risk HPV E6 proteins and immortalization-competent E6 mutants. ADA3 functions as a coactivator for p53-mediated transactivation by stabilizing p53 protein.
Alternative Name:
ADA3, ADA3 homolog, ADA3-like protein, FLJ20221, FLJ21329, hADA3, Transcriptional adaptor 3 (NGG1 homolog yeast) like, Transcriptional adaptor 3 like,
Application Dilution: WB: 1:500~1:2000
Specificity: TADA3L polyclonal antibody detects endogenous levels of TADA3L protein.
Immunogen:
Recombinant full length Human TADA3L.
MW: ~ 49 kDa
Swis Prot.: O75528
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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