TAF11 Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP19984a
Background:
Initiation of transcription by RNA polymerase II requiresthe activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymeraseproperly, serves as the scaffold for assembly of the remainder ofthe transcription complex, and acts as a channel for regulatorysignals. TFIID is composed of the TATA-binding protein (TBP) and agroup of evolutionarily conserved proteins known as TBP-associatedfactors or TAFs. TAFs may participate in basal transcription, serveas coactivators, function in promoter recognition or modify generaltranscription factors (GTFs) to facilitate complex assembly andtranscription initiation. This gene encodes a small subunit ofTFIID that is present in all TFIID complexes and interacts withTBP. This subunit also interacts with another small subunit, TAF13,to form a heterodimer with a structure similar to the histone corestructure.
Other Names:
Transcription initiation factor TFIID subunit 11, TFIID subunit p30-beta, Transcription initiation factor TFIID 28 kDa subunit, TAF(II)28, TAFII-28, TAFII28, TAF11, TAF2I
Target/Specificity:
The synthetic peptide sequence is selected from aa 8-21 of HUMAN TAF11
Gene Name: TAF11
Gene ID: 6882
Primary Accession: Q15544
Other Accession: NP_005634.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Initiation of transcription by RNA polymerase II requiresthe activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymeraseproperly, serves as the scaffold for assembly of the remainder ofthe transcription complex, and acts as a channel for regulatorysignals. TFIID is composed of the TATA-binding protein (TBP) and agroup of evolutionarily conserved proteins known as TBP-associatedfactors or TAFs. TAFs may participate in basal transcription, serveas coactivators, function in promoter recognition or modify generaltranscription factors (GTFs) to facilitate complex assembly andtranscription initiation. This gene encodes a small subunit ofTFIID that is present in all TFIID complexes and interacts withTBP. This subunit also interacts with another small subunit, TAF13,to form a heterodimer with a structure similar to the histone corestructure.
Other Names:
Transcription initiation factor TFIID subunit 11, TFIID subunit p30-beta, Transcription initiation factor TFIID 28 kDa subunit, TAF(II)28, TAFII-28, TAFII28, TAF11, TAF2I
Target/Specificity:
The synthetic peptide sequence is selected from aa 8-21 of HUMAN TAF11
Gene Name: TAF11
Gene ID: 6882
Primary Accession: Q15544
Other Accession: NP_005634.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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