TAF12 antibody (clone 10000000000), anti-human
€435.00
In stock
SKU
AC-AT4142a
Catalog Number: AC-AT4142a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT4142a">Request Information
Background:
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene.
Other Names:
Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID 20/15 kDa subunits, TAFII-20/TAFII-15, TAFII20/TAFII15, TAF12, TAF15, TAF2J, TAFII20
Antigen Type:
Recombinant Protein
Gene Name: TAF12 (HGNC:11545)
Gene ID: 6883
NCBI Accession: NP_001128690.1;NP_005635.1
Primary Accession: Q16514
Other Accession: BC011986
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene.
Other Names:
Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID 20/15 kDa subunits, TAFII-20/TAFII-15, TAFII20/TAFII15, TAF12, TAF15, TAF2J, TAFII20
Antigen Type:
Recombinant Protein
Gene Name: TAF12 (HGNC:11545)
Gene ID: 6883
NCBI Accession: NP_001128690.1;NP_005635.1
Primary Accession: Q16514
Other Accession: BC011986
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
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