TAF15 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14800a
Background:
Initiation of transcription by RNA polymerase II requiresthe activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymeraseproperly, serves as the scaffold for assembly of the remainder ofthe transcription complex, and acts as a channel for regulatorysignals. TFIID is composed of the TATA-binding protein (TBP) and agroup of evolutionarily conserved proteins known as TBP-associatedfactors or TAFs. TAFs may participate in basal transcription, serveas coactivators, function in promoter recognition or modify generaltranscription factors (GTFs) to facilitate complex assembly andtranscription initiation. This gene encodes a subunit of TFIIDpresent in a subset of TFIID complexes. Translocations involvingchromosome 17 and chromosome 9, where the gene for the nuclearreceptor CSMF is located, result in a gene fusion product that isan RNA binding protein associated with a subset of extraskeletalmyxoid chondrosarcomas. Two transcripts encoding different isoformshave been identified.
Other Names:
TATA-binding protein-associated factor 2N, 68 kDa TATA-binding protein-associated factor, TAF(II)68, TAFII68, RNA-binding protein 56, TAF15, RBP56, TAF2N
Gene Name: TAF15
Gene ID: 8148
Primary Accession: Q92804
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Initiation of transcription by RNA polymerase II requiresthe activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymeraseproperly, serves as the scaffold for assembly of the remainder ofthe transcription complex, and acts as a channel for regulatorysignals. TFIID is composed of the TATA-binding protein (TBP) and agroup of evolutionarily conserved proteins known as TBP-associatedfactors or TAFs. TAFs may participate in basal transcription, serveas coactivators, function in promoter recognition or modify generaltranscription factors (GTFs) to facilitate complex assembly andtranscription initiation. This gene encodes a subunit of TFIIDpresent in a subset of TFIID complexes. Translocations involvingchromosome 17 and chromosome 9, where the gene for the nuclearreceptor CSMF is located, result in a gene fusion product that isan RNA binding protein associated with a subset of extraskeletalmyxoid chondrosarcomas. Two transcripts encoding different isoformshave been identified.
Other Names:
TATA-binding protein-associated factor 2N, 68 kDa TATA-binding protein-associated factor, TAF(II)68, TAFII68, RNA-binding protein 56, TAF15, RBP56, TAF2N
Gene Name: TAF15
Gene ID: 8148
Primary Accession: Q92804
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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