TALDO1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8420
Background:
Proper cell growth, differentiation and survival relies on a series of enzymes involved in complex redox and metabolic pathways. One of these enzymes, Transaldolase, contributes to the generation of NADPH in the nonoxidative phase of the pentose phosphate pathway (PPP) and is important for maintaining metabolite balance. In conjunction with several other enzymes, Transaldolase works to maintain the mitochondrial transmembrane potential by producing both ribose-5-phosphate and NADPH for use in nucleic acid and lipid biosynthesis. The role of Transaldolase in the PPP of spermatoza is of significant importance, as deficiencies in Transaldolase are directly related with male infertility due to loss of sperm structure and function. Mutations in the gene encoding Transaldolase are thought to play a role in multiple sclerosis and are the direct cause of hepatosplenomegaly and telangiectases of the skin.
Alternative Name:
Transaldolase, TALDO1, TAL, TALDO, TALDOR
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: TALDO1 polyclonal antibody detects endogenous levels of TALDO1 protein.
Immunogen:
Recombinant full length Human TALDO1.
MW: ~ 38 kDa
Swis Prot.: P37837
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Proper cell growth, differentiation and survival relies on a series of enzymes involved in complex redox and metabolic pathways. One of these enzymes, Transaldolase, contributes to the generation of NADPH in the nonoxidative phase of the pentose phosphate pathway (PPP) and is important for maintaining metabolite balance. In conjunction with several other enzymes, Transaldolase works to maintain the mitochondrial transmembrane potential by producing both ribose-5-phosphate and NADPH for use in nucleic acid and lipid biosynthesis. The role of Transaldolase in the PPP of spermatoza is of significant importance, as deficiencies in Transaldolase are directly related with male infertility due to loss of sperm structure and function. Mutations in the gene encoding Transaldolase are thought to play a role in multiple sclerosis and are the direct cause of hepatosplenomegaly and telangiectases of the skin.
Alternative Name:
Transaldolase, TALDO1, TAL, TALDO, TALDOR
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: TALDO1 polyclonal antibody detects endogenous levels of TALDO1 protein.
Immunogen:
Recombinant full length Human TALDO1.
MW: ~ 38 kDa
Swis Prot.: P37837
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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