TAPBP polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7411
Background:
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Alternative Name:
NGS 17, NGS-17, NGS17, TAP associated protein, TAP binding protein, TAP binding protein (tapasin), TAP BP, TAP-associated protein, TAP-binding protein, TAPA, Tapasin, TAPBP, TPN, TPSN, TPSN_HUMAN,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: TAPBP polyclonal antibody detects endogenous levels of TAPBP protein.
Immunogen:
Recombinant full length Human TAPBP.
MW: ~47 kDa
Swis Prot.: O15533
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Alternative Name:
NGS 17, NGS-17, NGS17, TAP associated protein, TAP binding protein, TAP binding protein (tapasin), TAP BP, TAP-associated protein, TAP-binding protein, TAPA, Tapasin, TAPBP, TPN, TPSN, TPSN_HUMAN,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: TAPBP polyclonal antibody detects endogenous levels of TAPBP protein.
Immunogen:
Recombinant full length Human TAPBP.
MW: ~47 kDa
Swis Prot.: O15533
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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