TARBP2 antibody (clone 2G10), anti-human
€435.00
In stock
SKU
AC-AT4153a
Catalog Number: AC-AT4153a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
Request Information AC-AT4153a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
Request Information AC-AT4153a">Request Information
Background:
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Other Names:
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
Antigen Type:
Recombinant Protein
Gene Name: TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}
Gene ID: 6895
NCBI Accession: NP_004169.3;NP_599150.1;NP_599151.2
Primary Accession: Q15633
Other Accession: NM_134323
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Other Names:
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
Antigen Type:
Recombinant Protein
Gene Name: TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}
Gene ID: 6895
NCBI Accession: NP_004169.3;NP_599150.1;NP_599151.2
Primary Accession: Q15633
Other Accession: NM_134323
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review