TARBP2 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14108a
Background:
HIV-1, the causative agent of acquired immunodeficiencysyndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle.Activation of HIV-1 gene expression by the transactivator Tat isdependent on an RNA regulatory element (TAR) located downstream ofthe transcription initiation site. The protein encoded by this genebinds between the bulge and the loop of the HIV-1 TAR RNAregulatory element and activates HIV-1 gene expression in synergywith the viral Tat protein. Alternative splicing results inmultiple transcript variants encoding different isoforms. This genealso has a pseudogene.
Other Names:
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14108a was selected from the N-term region of TARBP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}
Gene ID: 6895
Primary Accession: Q15633
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
HIV-1, the causative agent of acquired immunodeficiencysyndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle.Activation of HIV-1 gene expression by the transactivator Tat isdependent on an RNA regulatory element (TAR) located downstream ofthe transcription initiation site. The protein encoded by this genebinds between the bulge and the loop of the HIV-1 TAR RNAregulatory element and activates HIV-1 gene expression in synergywith the viral Tat protein. Alternative splicing results inmultiple transcript variants encoding different isoforms. This genealso has a pseudogene.
Other Names:
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14108a was selected from the N-term region of TARBP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}
Gene ID: 6895
Primary Accession: Q15633
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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