TARBP2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8973
Background:
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Alternative Name:
RISC-loading complex subunit TARBP2UniRule annotation, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2, TRBP
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: TARBP2 polyclonal antibody detects endogenous levels of TARBP2 protein.
Immunogen:
Recombinant full length Human TARBP2.
MW: ~ 39kDa
Swis Prot.: Q15633
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Alternative Name:
RISC-loading complex subunit TARBP2UniRule annotation, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2, TRBP
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: TARBP2 polyclonal antibody detects endogenous levels of TARBP2 protein.
Immunogen:
Recombinant full length Human TARBP2.
MW: ~ 39kDa
Swis Prot.: Q15633
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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