TARDBP antibody (clone 2E2-D3), anti-human
€435.00
In stock
SKU
AC-AT4154a
Catalog Number: AC-AT4154a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, IP
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, IP
Request Information AC-AT4154a">Request Information
Background:
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
Other Names:
TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43
Antigen Type:
Recombinant Protein
Gene Name: TARDBP {ECO:0000303|PubMed:18396105, ECO:0000312|HGNC:HGNC:11571}
Gene ID: 23435
NCBI Accession: NP_031401.1
Primary Accession: Q13148
Other Accession: BC001487
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
Other Names:
TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43
Antigen Type:
Recombinant Protein
Gene Name: TARDBP {ECO:0000303|PubMed:18396105, ECO:0000312|HGNC:HGNC:11571}
Gene ID: 23435
NCBI Accession: NP_031401.1
Primary Accession: Q13148
Other Accession: BC001487
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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