TARDBP Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13763a
Background:
HIV-1, the causative agent of acquired immunodeficiencysyndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle.Activation of HIV-1 gene expression by the transactivator Tat isdependent on an RNA regulatory element (TAR) located downstream ofthe transcription initiation site. The protein encoded by this geneis a transcriptional repressor that binds to chromosomallyintegrated TAR DNA and represses HIV-1 transcription. In addition,this protein regulates alternate splicing of the CFTR gene. Asimilar pseudogene is present on chromosome 20. [provided byRefSeq].
Other Names:
TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13763a was selected from the N-term region of TARDBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TARDBP {ECO:0000303|PubMed:18396105, ECO:0000312|HGNC:HGNC:11571}
Gene ID: 23435
Primary Accession: Q13148
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
HIV-1, the causative agent of acquired immunodeficiencysyndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle.Activation of HIV-1 gene expression by the transactivator Tat isdependent on an RNA regulatory element (TAR) located downstream ofthe transcription initiation site. The protein encoded by this geneis a transcriptional repressor that binds to chromosomallyintegrated TAR DNA and represses HIV-1 transcription. In addition,this protein regulates alternate splicing of the CFTR gene. Asimilar pseudogene is present on chromosome 20. [provided byRefSeq].
Other Names:
TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13763a was selected from the N-term region of TARDBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TARDBP {ECO:0000303|PubMed:18396105, ECO:0000312|HGNC:HGNC:11571}
Gene ID: 23435
Primary Accession: Q13148
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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