Tau (clone TAU-2), anti-human, bovine

Background:
The microtubule-associated proteins(MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles(NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau(MTBT1) is mapped to chromosome 17q21.

Decription:
Mouse IgG monoclonal antibody for Tau, microtubule-associated protein tau (MAPT) detection. Tested with WB, IHC-P in Human, bovine. No cross reactivity with other proteins.

Synonyms: DDPAC, MAPTL, PHF-tau, FLJ31424, FTDP-17, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU, G protein beta1/gamma2 subunit-interacting factor 1, microtubule-associated protein tau, isoform 4, Neurofibrillary tangle protein, Paired helical filament-tau

Clone: TAU-2

Isotype: Mouse IgG1

Immunogen: Bovine microtubule-associated proteins(MAPs).

Reactivity: human, bovine

Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Applications: WB, IHC-P

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.