TBCC Antibody (N-term ) Blocking peptide

Background:
Cofactor C is one of four proteins (cofactors A, D, E, andC) involved in the pathway leading to correctly folded beta-tubulinfrom folding intermediates. Cofactors A and D are believed to playa role in capturing and stabilizing beta-tubulin intermediates in aquasi-native confirmation. Cofactor E binds to the cofactorD/beta-tubulin complex; interaction with cofactor C then causes therelease of beta-tubulin polypeptides that are committed to thenative state.

Other Names:
Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC, TBCC

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13475a was selected from the N-term region of TBCC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: TBCC

Gene ID: 6903
Primary Accession: Q15814
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.