TBL1X antibody (clone 2B6), anti-human
€435.00
In stock
SKU
AC-AT4162a
Catalog Number: AC-AT4162a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: IHC, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: IHC, E
Request Information AC-AT4162a">Request Information
Background:
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Other Names:
F-box-like/WD repeat-containing protein TBL1X, SMAP55, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked, TBL1X, TBL1
Antigen Type:
Recombinant Protein
Gene Name: TBL1X
Gene ID: 6907
NCBI Accession: NP_001132938.1;NP_001132939.1;NP_001132940.1;NP_005638.1
Primary Accession: O60907
Other Accession: NM_005647
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Other Names:
F-box-like/WD repeat-containing protein TBL1X, SMAP55, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked, TBL1X, TBL1
Antigen Type:
Recombinant Protein
Gene Name: TBL1X
Gene ID: 6907
NCBI Accession: NP_001132938.1;NP_001132939.1;NP_001132940.1;NP_005638.1
Primary Accession: O60907
Other Accession: NM_005647
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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