TBLR1 (clone 4F3-A8-D9), anti-human, mouse

Background:
TBLR1 is an F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. It plays an essential role in transcription activation mediated by nuclear receptors and probably acts as an integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of the N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Synonyms: C21, DC42, IRA1, MRD41, TBLR1, C21, DC42, IRA1, TBLR1

Cellular Location: Nucleus

Immunogen:
Purified recombinant human TBLR1 protein fragments expressed in E.coli.

Gene Symbol: TBLR1

Gene ID: 79718

Swiss prot: Q9BZK7

Calculated MW: 60kDa

Recommended dilution:
WB 1:1000, IHC 1:200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.